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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
22.73
Human Site:
Y213
Identified Species:
35.71
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
Y213
G
Q
N
G
Q
K
K
Y
Q
I
N
L
K
S
H
Chimpanzee
Pan troglodytes
XP_511025
426
45548
Y198
G
L
N
G
Q
K
K
Y
Q
I
H
L
K
S
V
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
Y213
G
Q
N
G
Q
K
K
Y
Q
I
N
L
K
S
H
Dog
Lupus familis
XP_853833
304
33793
N175
G
Q
K
K
Y
Q
I
N
L
K
S
H
S
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
Y203
G
Q
N
G
Q
K
K
Y
Q
I
N
L
K
S
H
Rat
Rattus norvegicus
Q62814
300
33206
S174
K
Y
Q
I
N
L
K
S
H
S
G
P
I
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
I100
N
G
Q
K
K
Y
Q
I
N
L
K
S
H
S
G
Chicken
Gallus gallus
Q90977
403
43534
V272
S
T
Q
G
P
I
D
V
F
L
C
P
E
D
S
Frog
Xenopus laevis
NP_001086706
375
40890
F175
N
T
N
G
Q
K
K
F
Q
I
H
L
K
S
T
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
Y175
H
V
N
G
Q
K
K
Y
Q
I
H
L
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
Q531
N
Q
Q
Q
Q
Q
Q
Q
Q
Q
L
L
Q
Q
P
Honey Bee
Apis mellifera
XP_624285
300
34327
D174
T
Q
T
S
E
E
D
D
K
E
I
N
Y
E
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
R223
Q
R
I
T
R
A
S
R
L
V
P
A
E
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
Y294
N
D
Y
P
Q
R
R
Y
R
I
V
L
R
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
Y330
A
D
H
P
Q
R
R
Y
R
I
I
L
R
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
80
100
13.3
N.A.
100
6.6
N.A.
6.6
6.6
66.6
73.3
N.A.
26.6
6.6
N.A.
0
P-Site Similarity:
100
86.6
100
26.6
N.A.
100
6.6
N.A.
26.6
20
80
80
N.A.
46.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
14
0
0
0
0
14
7
0
0
0
0
0
7
0
% D
% Glu:
0
0
0
0
7
7
0
0
0
7
0
0
14
7
0
% E
% Phe:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% F
% Gly:
34
7
0
47
0
0
0
0
0
0
7
0
0
7
7
% G
% His:
7
0
7
0
0
0
0
0
7
0
20
7
7
7
20
% H
% Ile:
0
0
7
7
0
7
7
7
0
54
14
0
7
0
7
% I
% Lys:
7
0
7
14
7
40
47
0
7
7
7
0
40
0
0
% K
% Leu:
0
7
0
0
0
7
0
0
14
14
7
60
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
27
0
40
0
7
0
0
7
7
0
20
7
0
0
0
% N
% Pro:
0
0
0
14
7
0
0
0
0
0
7
14
0
7
14
% P
% Gln:
7
40
27
7
60
14
14
7
47
7
0
0
7
7
0
% Q
% Arg:
0
7
0
0
7
14
14
7
14
0
0
0
14
0
0
% R
% Ser:
7
0
0
7
0
0
7
7
0
7
7
7
7
60
14
% S
% Thr:
7
14
7
7
0
0
0
0
0
0
0
0
0
0
20
% T
% Val:
0
7
0
0
0
0
0
7
0
7
7
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
7
0
7
7
0
47
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _